GOAL Create an explainer series covering Bayer’s NUBEQA treatment for nonmetastatic castration-resistant prostate cancer (nmCRPC). The purpose of the series was to inform prescribers and caregivers on the Challenge Our challenge was to create a campaign for Bayer’s treatment that would be narratively compelling and visually exciting, while working within the strict guidelines of pharmaceutical advertising regulation. Our Approach In order to stay within the regulatory guidelines the campaign was split into two parts; branded, and unbranded. Branded videos could utilize the NUBEQA brand guidelines provided by Bayer, while unbranded videos would use similar visual elements but remain distanced from the NUBEQA treatment. Branded videos would specifically reference the NUBEQA treatment, and would thereby require less specific claims, and for elements like Indication, Important Safety Information, and points of context to be added throughout the video. Unbranded videos would serve as educational content, speak more generally to caregivers about nmCRPC and be able to speak more Branded Tolerability and Efficacy For the Tolerability and Efficacy installments of the series we chose a visual approach which combined live-action footage with text and other animated elements. By taking this approach we were able to add a strong element of humanity to the videos. Showing men in different age groups spending quality time with their family and loved ones created the opportunity to show the benefits of the NUBEQA treatment, and remind caregivers what the goal Each video was accompanied by powerful, motivational music that matched up to the bold and strong visuals associated with the NUBEQA Branded Accessibilty For the accessibility videos, we took an approach that utilized fully custom illustrative animation with a more fluid and expressionistic style. We chose to animate these videos this way in order to better integrate the finer details and data points which outlined the accessibility of NUBEQA treatment. This set of three videos were accompanied by upbeat music and voiceover narration, and each followed parts of the doctor-patient journey, weaving into and out of sequences of data, icon animation, and text on screen. This approach gave the